Novel Monofunctional Histidinol-Phosphate Phosphatase of the DDDD Superfamily of Phosphohydrolases
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چکیده
منابع مشابه
Novel monofunctional histidinol-phosphate phosphatase of the DDDD superfamily of phosphohydrolases.
The TON_0887 gene was identified as the missing histidinol-phosphate phosphatase (HolPase) in the hyperthermophilic archaeon "Thermococcus onnurineus" NA1. The protein contained conserved motifs of the DDDD superfamily of phosphohydrolase, and the recombinantly expressed protein exhibited strong HolPase activity. In this study, we functionally assessed for the first time the monofunctional DDDD...
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15 صفحه اولSome properties of the catalytic sites of imidazoleglycerol phosphate dehydratase-histidinol phosphate phosphatase, a bifunctional enzyme from Salmonella typhimurium.
Kinetic and aggregatory properties of a partially purified preparation of D-erythro-imidazoleglycerol phosphate dehydratase-histidinol phosphate phosphatase from a derepressed mutant of Salmonella typhimurium (his012$2) have been investigated. The molecular weight in crude extracts is 300,000. Purification of the enzyme causes disaggregation, the main component keing 75,000 in molecular weight....
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2008
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.01722-07